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Coiled-coil domain containing 42 (Ccdc42) is necessary for proper sperm development and male fertility in the mouse.
Pasek RC, Malarkey E, Berbari NF, Sharma N, Kesterson RA, Tres LL, Kierszenbaum AL, Yoder BK. Pasek RC, et al. Dev Biol. 2016 Apr 15;412(2):208-18. doi: 10.1016/j.ydbio.2016.01.042. Epub 2016 Mar 3. Dev Biol. 2016. PMID: 26945718 Free PMC article.
Here, we provide data indicating that mutations in the gene Coiled-coil domain containing 42 (Ccdc42) is associated with malformation of the mouse sperm flagella. ...Male mice homozygous for a loss-of-function Ccdc42 allele (Ccd
Here, we provide data indicating that mutations in the gene Coiled-coil domain containing 42 (Ccdc42
CCDC38 is required for sperm flagellum biogenesis and male fertility in mice.
Zhang R, Wu B, Liu C, Zhang Z, Wang X, Wang L, Xiao S, Chen Y, Wei H, Jiang H, Gao F, Yuan L, Li W. Zhang R, et al. Development. 2022 Jun 1;149(11):dev200516. doi: 10.1242/dev.200516. Epub 2022 Jun 13. Development. 2022. PMID: 35587122
The sperm flagellum is essential for male fertility, and defects in flagellum biogenesis are associated with male infertility. Deficiency of coiled-coil domain-containing (CCDC) 42 (CCDC42) is specifically associated with malformation of …
The sperm flagellum is essential for male fertility, and defects in flagellum biogenesis are associated with male infertility. Deficiency of …
CCDC42 Localizes to Manchette, HTCA and Tail and Interacts With ODF1 and ODF2 in the Formation of the Male Germ Cell Cytoskeleton.
Tapia Contreras C, Hoyer-Fender S. Tapia Contreras C, et al. Front Cell Dev Biol. 2019 Aug 14;7:151. doi: 10.3389/fcell.2019.00151. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31475146 Free PMC article.
Amongst all candidate proteins affecting the HTCA when missing, the structural protein CCDC42 attracted our attention. The coiled-coil domain containing 42 (CCDC42) is important for HTCA and sperm tail formation but is other …
Amongst all candidate proteins affecting the HTCA when missing, the structural protein CCDC42 attracted our attention. The …